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Cobalt(III)-Catalyzed C-H Activation: Counter Anion Triggered Desilylative Direct ortho-Vinylation of Secondary Benzamides

Muniraj, Nachimuthu and Prabhu, Kandikere Ramaiah (2018) Cobalt(III)-Catalyzed C-H Activation: Counter Anion Triggered Desilylative Direct ortho-Vinylation of Secondary Benzamides. In: ADVANCED SYNTHESIS & CATALYSIS, 360 (18). pp. 3579-3584.

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Official URL: http://dx.doi.org/10.1002/adsc.201800649

Abstract

A Co(III)-catalyzed counter anion triggered desilylative direct ortho-vinylation of secondary benzamides is reported. The reaction furnishes the alkenylated product, exclusively, and no formation of the possible cyclic products was observed. Mechanistic studies suggest that the counter anion, SbF6](-), plays a crucial role in the desilylation. The utility of alkynylsilanes instead of terminal alkynes turned out to be a potential and practical approach to obtain the corresponding vinylated products. The developed methodology is compatible with a variety of functional groups.

Item Type: Journal Article
Additional Information: Copy right for this article belong to WILEY-V C H VERLAG GMBH
Keywords: Cobalt; amides; alkynylsilane; desilylation; alkenylation; C-H activation
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Depositing User: Id for Latest eprints
Date Deposited: 03 Oct 2018 14:03
Last Modified: 03 Oct 2018 14:03
URI: http://eprints.iisc.ac.in/id/eprint/60796

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