ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Iridium-catalyzed enantioselective direct vinylogous allylic alkylation of coumarins

Sarkar, Rahul and Mitra, Sankash and Mukherjee, Santanu (2018) Iridium-catalyzed enantioselective direct vinylogous allylic alkylation of coumarins. In: CHEMICAL SCIENCE, 9 (26). pp. 5767-5772.

[img] PDF
Che_Sci_9-26_5767_2018.pdf - Published Version
Restricted to Registered users only

Download (1MB) | Request a copy
Official URL: https://dx.doi.org/10.1039/c8sc02041h

Abstract

The first iridium-catalyzed enantioselective vinylogous allylic alkylation of coumarins is presented. Using easily accessible linear allylic carbonates as the allylic electrophile, this reaction installs unfunctionalized allyl groups at the -position of 4-methylcoumarins in an exclusively branched-selective manner generally in high yields with an excellent level of enantioselectivity (up to 99:1 er).

Item Type: Journal Article
Additional Information: Copyright of this article belong to ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Depositing User: Id for Latest eprints
Date Deposited: 24 Jul 2018 14:54
Last Modified: 24 Jul 2018 14:54
URI: http://eprints.iisc.ac.in/id/eprint/60279

Actions (login required)

View Item View Item