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Continuous stacking computational approach based automated microscope slide scanner

Murali, Swetha and Adhikari, Jayesh Vasudeva and Jagannadh, Veerendra Kalyan and Gorthi, Sai Siva (2018) Continuous stacking computational approach based automated microscope slide scanner. In: REVIEW OF SCIENTIFIC INSTRUMENTS, 89 (2).

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Official URL: http://dx.doi.org/10.1063/1.5022549

Abstract

Cost-effective and automated acquisition of whole slide images is a bottleneck for wide-scale deployment of digital pathology. In this article, a computation augmented approach for the development of an automated microscope slide scanner is presented. The realization of a prototype device built using inexpensive off-the-shelf optical components and motors is detailed. The applicability of the developed prototype to clinical diagnostic testing is demonstrated by generating good quality digital images of malaria-infected blood smears. Further, the acquired slide images have been processed to identify and count the number of malaria-infected red blood cells and thereby perform quantitative parasitemia level estimation. The presented prototype would enable cost-effective deployment of slide-based cyto-diagnostic testing in endemic areas. Published by AIP Publishing.

Item Type: Journal Article
Additional Information: Copy right for the article belong to AMER INST PHYSICS, 1305 WALT WHITMAN RD, STE 300, MELVILLE, NY 11747-4501 USA
Department/Centre: Division of Physical & Mathematical Sciences > Instrumentation Appiled Physics
Depositing User: Id for Latest eprints
Date Deposited: 27 Mar 2018 18:27
Last Modified: 27 Mar 2018 18:27
URI: http://eprints.iisc.ac.in/id/eprint/59398

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