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Ulvan-chitosan polyelectrolyte complexes as matrices for enzyme induced biomimetic mineralization

Dash, Mamoni and Samal, Sangram K and Morelli, Andrea and Bartoli, Cristina and Declercq, Heidi A and Douglas, Timothy EL and Dubruel, Peter and Chiellini, Federica (2018) Ulvan-chitosan polyelectrolyte complexes as matrices for enzyme induced biomimetic mineralization. In: CARBOHYDRATE POLYMERS, 182 . pp. 254-264.

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Official URL: http://dx.doi.org/10.1016/j.carbpol.2017.11.016

Abstract

Polyelectrolyte complexes (PEC) of chitosan and ulvan were fabricated to study alkaline phosphatase ( ALP) mediated formation of apatitic minerals. Scaffolds of the PEC were subjected to ALP and successful mineral formation was studied using SEM, Raman and XRD techniques. Investigation of the morphology via SEM shows globular structures of the deposited minerals, which promoted cell attachment, proliferation and extracellular matrix formation. The PEC and their successful calcium phosphate based mineralization offers a greener route of scaffold fabrication towards developing resorbable materials for tissue engineering.

Item Type: Journal Article
Additional Information: Copy right for this article belongs to the ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND
Department/Centre: Division of Chemical Sciences > Materials Research Centre
Depositing User: review EPrints Reviewer
Date Deposited: 12 Jan 2018 09:40
Last Modified: 12 Jan 2018 09:40
URI: http://eprints.iisc.ac.in/id/eprint/58639

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