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A molecular beacon-based DNA switch for reversible pH sensing in vesicles and live cells

Narayanaswamy, Nagarjun and Nair, Raji R and Suseela, YV and Saini, Deepak Kumar and Govindaraju, T (2016) A molecular beacon-based DNA switch for reversible pH sensing in vesicles and live cells. In: CHEMICAL COMMUNICATIONS, 52 (56). pp. 8741-8744.

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Official URL: http://dx.doi.org/10.1039/c6cc02705a

Abstract

In this Communication, a molecular beacon-based DNA switch (LMB) is developed as an efficient and reversible pH sensing probe. Remarkably, LMB exhibited reversible structural transition between the closed (molecular beacon) and open (A-motif) states very efficiently in synthetic vesicles and live cells without the need for any transfection agents.

Item Type: Journal Article
Additional Information: Copy right for this article belongs to the ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Department/Centre: Division of Biological Sciences > Molecular Reproduction, Development & Genetics
Depositing User: Id for Latest eprints
Date Deposited: 22 Aug 2016 09:48
Last Modified: 22 Aug 2016 09:48
URI: http://eprints.iisc.ac.in/id/eprint/54501

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