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Diffractive Optical Analysis for Refractive Index Sensing using Transparent Phase Gratings

Kumawat, Nityanand and Pal, Parama and Varma, Manoj (2015) Diffractive Optical Analysis for Refractive Index Sensing using Transparent Phase Gratings. In: SCIENTIFIC REPORTS, 5 .

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Official URL: http://dx.doi.org/10.1038/srep16687

Abstract

We report the implementation of a micro-patterned, glass-based photonic sensing element that is capable of label-free biosensing. The diffractive optical analyzer is based on the differential response of diffracted orders to bulk as well as surface refractive index changes. The differential read-out suppresses signal drifts and enables time-resolved determination of refractive index changes in the sample cell. A remarkable feature of this device is that under appropriate conditions, the measurement sensitivity of the sensor can be enhanced by more than two orders of magnitude due to interference between multiply reflected diffracted orders. A noise-equivalent limit of detection (LoD) of 6 x 10(-7) was achieved with this technique with scope for further improvement.

Item Type: Journal Article
Additional Information: Copy right for this article belongs to the NATURE PUBLISHING GROUP, MACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND
Department/Centre: Division of Electrical Sciences > Electrical Communication Engineering
Division of Interdisciplinary Research > Centre for Nano Science and Engineering
Depositing User: Id for Latest eprints
Date Deposited: 10 Dec 2015 05:55
Last Modified: 26 Nov 2018 15:15
URI: http://eprints.iisc.ac.in/id/eprint/52867

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