Lanke, Veeranjaneyulu and Bettadapur, Kiran R and Prabhu, Kandikere Ramaiah (2015) Site-Selective Addition of Maleimide to Indole at the C-2 Position: Ru(II)-Catalyzed C-H Activation. In: ORGANIC LETTERS, 17 (19). pp. 4662-4665.
PDF
Org_Let_17-19_4662_2015.pdf - Published Version Restricted to Registered users only Download (1MB) | Request a copy |
Official URL: http://dx.doi.org/10.1021/acs.orglett.5b01809
Abstract
Synthesis of 3-(indol-2-yl)succinimide derivatives is presented using a directing group strategy. Selective functionalization of C-2 in the presence of highly reactive C-3 in indole derivatives has been achieved. A conjugate addition product instead of Heck-type product has been brought about by careful selection of the alkene partner (maleimides and maleate esters) such that a beta-hydride elimination is avoided.
Item Type: | Journal Article |
---|---|
Publication: | ORGANIC LETTERS |
Publisher: | AMER CHEMICAL SOC |
Additional Information: | Copy right for this article belongs to the AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA |
Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
Date Deposited: | 02 Nov 2015 05:20 |
Last Modified: | 02 Nov 2015 05:20 |
URI: | http://eprints.iisc.ac.in/id/eprint/52680 |
Actions (login required)
View Item |