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Enantio sensing property of helicin, the derivative of a natural product: Discrimination of amines and amino alcohols

Kumari, Divya and Sachin, SL and Suryaprakash, N (2015) Enantio sensing property of helicin, the derivative of a natural product: Discrimination of amines and amino alcohols. In: CHEMICAL PHYSICS LETTERS, 636 . pp. 72-77.

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Official URL: http://dx.doi.org/10.1016/j.cplett.2015.07.023

Abstract

The chiral sensing property of helicin (the derivative of natural product obtained by partial oxidation of salicin, extracted from willow tree (Salix helix)) is reported. The use of helicin as a chiral derivatizing agent for the discrimination of amines and amino alcohols is convincingly established using H-1 NMR spectroscopy. The large chemical shift separation achieved between the discriminated peaks facilitated the accurate quantification of enantiomeric composition. The consistent trend observed in the shifting of imine proton peak (Delta delta) of helicin in all the derivatized molecules might aid the determination of spatial configuration. (C) 2015 Elsevier B.V. All rights reserved.

Item Type: Journal Article
Additional Information: Copy right for this article belongs to the ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
Department/Centre: Division of Chemical Sciences > NMR Research Centre (Formerly Sophisticated Instruments Facility)
Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Depositing User: Id for Latest eprints
Date Deposited: 30 Oct 2015 06:41
Last Modified: 30 Oct 2015 06:41
URI: http://eprints.iisc.ac.in/id/eprint/52654

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