Viruses and viral proteins

Verdaguer, Nuria and Ferrero, Diego and Murthy, Mathur RN (2014) Viruses and viral proteins. In: IUCRJ, 1 (6). pp. 492-504.

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Abstract

For more than 30 years X-ray crystallography has been by far the most powerful approach for determining the structures of viruses and viral proteins at atomic resolution. The information provided by these structures, which covers many important aspects of the viral life cycle such as cell-receptor recognition, viral entry, nucleic acid transfer and genome replication, has extensively enriched our vision of the virus world. Many of the structures available correspond to potential targets for antiviral drugs against important human pathogens. This article provides an overview of the current knowledge of different structural aspects of the above-mentioned processes.

Item Type:	Journal Article
Publication:	IUCRJ
Publisher:	INT UNION CRYSTALLOGRAPHY
Additional Information:	Copy right for this article belongs to the INT UNION CRYSTALLOGRAPHY, 2 ABBEY SQ, CHESTER, CH1 2HU, ENGLAND
Keywords:	bacteriophages; genome delivery; fusion proteins; RNA-dependent RNA polymerases; viral proteases; viral receptors; viruses
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	31 Jul 2015 14:07
Last Modified:	31 Jul 2015 14:07
URI:	http://eprints.iisc.ac.in/id/eprint/51973

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