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Iodine promoted alpha-hydroxylation of ketones

Siddaraju, Yogesh and Prabhu, Kandikere Ramaiah (2015) Iodine promoted alpha-hydroxylation of ketones. In: ORGANIC & BIOMOLECULAR CHEMISTRY, 13 (24). pp. 6749-6753.

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Official URL: http://dx.doi.org/ 10.1039/c5ob00684h

Abstract

A novel method for alpha-hydroxylation of ketones using substoichiometric amount of iodine under metalfree conditions is described. This method has been successfully employed in synthesizing a variety of heterocyclic compounds, which are useful precursors. alpha-Hydroxylation of diketones and triketones are illustrated. This strategy provides a novel, efficient, mild and inexpensive method for alpha-hydroxylation of aryl ketones using a sub-stoichiometric amount of molecular iodine.

Item Type: Journal Article
Additional Information: Copy right for this article belongs to the ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Depositing User: Id for Latest eprints
Date Deposited: 19 Jul 2015 09:42
Last Modified: 19 Jul 2015 09:42
URI: http://eprints.iisc.ac.in/id/eprint/51899

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