CH-RES-TOCSY: Enantiomers spectral resolution and measurement of heteronuclear residual dipolar couplings

Lokesh, N and Suryaprakash, N (2015) CH-RES-TOCSY: Enantiomers spectral resolution and measurement of heteronuclear residual dipolar couplings. In: CHEMICAL PHYSICS LETTERS, 625 . pp. 10-13.

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Abstract

A new 2D NMR technique cited as CH-RES-TOCSY, for complete unraveling the spectra of enantiomers and for the measurement of structurally important C-HRDC sis reported. The spectral overlap and complexity of peaks were reduced by the blend of selective excitation and homo-decoupling. Differential values of C-H RDCs of enantiomers (R and S) are exploited to separate the enantiomeric peaks. The complete unraveling of the spectra of both the enantiomers is achieved by incorporating a TOCSY mixing blockprior to signal acquisition. The additional application of the method is demonstrated for the assignment of symmetric isomers. (C) 2015 Elsevier B.V. All rights reserved.

Item Type:	Journal Article
Publication:	CHEMICAL PHYSICS LETTERS
Publisher:	ELSEVIER SCIENCE BV
Additional Information:	Copy right for this article belongs to the ELSEVIER SCIENCE BV, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
Keywords:	POLYPEPTIDE LIQUID-CRYSTALS; DEUTERIUM NMR-SPECTROSCOPY; ABSOLUTE-CONFIGURATION; CHIRAL SEPARATIONS; ASSIGNMENT; MOLECULES; HYDROCARBONS; ANISOTROPY; ISOMERS
Department/Centre:	Division of Chemical Sciences > Solid State & Structural Chemistry Unit
Date Deposited:	28 Apr 2015 07:30
Last Modified:	28 Apr 2015 07:30
URI:	http://eprints.iisc.ac.in/id/eprint/51424

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