Combined inhalation and oral supplementation of Vitamin A and Vitamin D: A possible prevention and therapy for tuberculosis

Syal, Kirtimaan and Chakraborty, Surajit and Bhattacharyya, Rajasri and Banerjee, Dibyajyoti (2015) Combined inhalation and oral supplementation of Vitamin A and Vitamin D: A possible prevention and therapy for tuberculosis. In: MEDICAL HYPOTHESES, 84 (3). pp. 199-203.

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Abstract

Tuberculosis is continuing as a problem of mankind. With evolution, MDR and XDR forms of tuberculosis have emerged from drug sensitive strain. MDR and XDR strains are resistant to most of the antibiotics, making the management more difficult. BCG vaccine is not providing complete protection against tuberculosis. Therefore new infections are spreading at a tremendous rate. At the present moment there is experimental evidence to believe that Vitamin A and Vitamin D has anti-mycobacterial property. It is in this context, we have hypothesized a host based approach using the above vitamins that can cause possible prevention and cure of tuberculosis with minimal chance of resistance or toxicity. (C) 2015 Elsevier Ltd. All rights reserved.

Item Type:	Journal Article
Publication:	MEDICAL HYPOTHESES
Publisher:	CHURCHILL LIVINGSTONE
Additional Information:	Copy right for this article belongs to the CHURCHILL LIVINGSTONE, JOURNAL PRODUCTION DEPT, ROBERT STEVENSON HOUSE, 1-3 BAXTERS PLACE, LEITH WALK, EDINBURGH EH1 3AF, MIDLOTHIAN, SCOTLAND
Keywords:	CULTURED HUMAN MACROPHAGES; VIRULENT TUBERCLE-BACILLI; TACO GENE-TRANSCRIPTION; STAGE RENAL-DISEASE; MYCOBACTERIUM-TUBERCULOSIS; RETINOIC ACID; PATHOGENIC MYCOBACTERIA; PULMONARY TUBERCULOSIS; INTRACELLULAR SURVIVAL; ANTIMICROBIAL ACTIVITY
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	20 Apr 2015 11:27
Last Modified:	20 Apr 2015 11:27
URI:	http://eprints.iisc.ac.in/id/eprint/51301

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