ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Organocatalytic Enantioselective Formal C(sp(2))-H Alkylation

Manna, Madhu Sudan and Mukherjee, Santanu (2015) Organocatalytic Enantioselective Formal C(sp(2))-H Alkylation. In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137 (1). pp. 130-133.

[img] PDF
jou_ame_che_soc_137-1_130_2015.pdf - Published Version
Restricted to Registered users only

Download (1MB) | Request a copy
Official URL: http://dx.doi.org/ 10.1021/ja5117556

Abstract

An organocatalytic enantioselective formal C(sp(2))-H alkylation is reported. This alkylative desymmetrization of prochiral 2,2-disubstituted cyclopentene-1,3-dione is catalyzed by a bifunctional tertiary aminourea derivative, utilizes air-stable and inexpensive nitroalkanes as the alkylating agents, and delivers synthetically versatile five-membered carbocycles containing an all-carbon quaternary stereogenic center remote from the reaction site in excellent enantioselectivity.

Item Type: Journal Article
Additional Information: Copyright for this article belongs to the AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Depositing User: Id for Latest eprints
Date Deposited: 19 Mar 2015 12:08
Last Modified: 19 Mar 2015 12:08
URI: http://eprints.iisc.ac.in/id/eprint/51049

Actions (login required)

View Item View Item