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Synthesis of Azepino4,5-b]indolones by an Intramolecular Cyclization of Unsaturated Tryptamides

Nidhiry, John Eugene and Prasad, Kavirayani R (2014) Synthesis of Azepino4,5-b]indolones by an Intramolecular Cyclization of Unsaturated Tryptamides. In: SYNLETT, 25 (18). pp. 2585-2590.

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Official URL: http://dx.doi.org/ 10.1055/s-0034-1379083

Abstract

A facile general route for the synthesis of azepino4,5-b]indolones is presented. The strategy involves a Bronsted acid assisted intramolecular cyclization of unsaturated tryptamides. The methodology developed has been applied to the synthesis of the ABCD tetracyclic core of the natural product tronocarpine.

Item Type: Journal Article
Additional Information: Copyright for this article belongs to the GEORG THIEME VERLAG KG, RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
Keywords: alkaloids; azepino4,5-b]indolone; tronocarpine; tryptamide; ethyl lactate
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Depositing User: Id for Latest eprints
Date Deposited: 20 Dec 2014 04:35
Last Modified: 20 Dec 2014 04:35
URI: http://eprints.iisc.ac.in/id/eprint/50477

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