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Born-ratio type data normalization improves quantitation in photoacoustic tomography

Singh, Suheshkumar M and Yalavarthy, Phaneendra K (2014) Born-ratio type data normalization improves quantitation in photoacoustic tomography. In: Conference on Medical Imaging - Ultrasonic Imaging and Tomography, FEB 18-20, 2014, San Diego, CA.

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Official URL: http://dx.doi.org/ 10.1117/12.2035213

Abstract

In this report, we present a Born-ratio type of data normalization for reconstruction of initial acoustic pressure distribution in photoacoustic tomography (PAT). The normalized Born-ratio type of data is obtained as a ratio of photoacoustic pressure obtained with tissue sample in a coupling medium to the one obtained using purely coupling medium. It is shown that this type of data normalization improves the quantitation (intrinsic contrast) of the reconstructed images in comparison to the traditional techniques (unnormalized) that are currently available in PAT. Studies are carried out using various tissue samples. The robustness of the proposed method is studied at various noise levels added to the collected data. The improvement in quantitation can enable accurate estimation of pathophysiological parameter (optical absorption coefficient, a) of tissue sample under investigation leading to better sensitivity in PAT.

Item Type: Conference Proceedings
Additional Information: Copy right for this article belongs to the SPIE-INT SOC OPTICAL ENGINEERING, 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
Department/Centre: Division of Interdisciplinary Research > Supercomputer Education & Research Centre
Depositing User: Id for Latest eprints
Date Deposited: 22 Aug 2014 11:38
Last Modified: 22 Aug 2014 11:38
URI: http://eprints.iisc.ac.in/id/eprint/49705

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