Rokade, Balaji V and Gadde, Karthik and Prabhu, Kandikere Ramaiah (2014) Copper-Catalyzed Oxidative Transformation of Secondary Alcohols to 1,5-Disubstituted Tetrazoles. In: ADVANCED SYNTHESIS & CATALYSIS, 356 (5). pp. 946-950.
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Official URL: http://dx.doi.org/10.1002/adsc.201300863
Abstract
A mild and convenient oxidative transformation of secondary alcohols to 1,5-disubstituted tetrazoles is uncovered by employing trimethylsilyl azide (TMSN3) as a nitrogen source in the presence of a catalytic amount of copper(II) perchlorate hexahydrate Cu(ClO4)(2)(.)6H(2)O] (5mol%) and 2,3-dichloro-5,6-dicyano-para-benzoquinone (DDQ) (1.2equiv.) as an oxidant. This reaction is performed under ambient conditions and proceeds through CC bond cleavage.
Item Type: | Journal Article |
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Publication: | ADVANCED SYNTHESIS & CATALYSIS |
Publisher: | WILEY-V C H VERLAG GMBH |
Additional Information: | Copyright for this article belongs to the WILEY-V C H VERLAG GMBH, GERMANY |
Keywords: | alcohols; azides; copper; regioselectivity; tetrazoles |
Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
Date Deposited: | 19 May 2014 05:28 |
Last Modified: | 19 May 2014 05:28 |
URI: | http://eprints.iisc.ac.in/id/eprint/49101 |
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