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Remarkable influence of secondary catalyst site on enantioselective desymmetrization of cyclopentenedione

Manna, Madhu Sudan and Mukherjee, Santanu (2014) Remarkable influence of secondary catalyst site on enantioselective desymmetrization of cyclopentenedione. In: CHEMICAL SCIENCE, 5 (4). pp. 1627-1633.

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Official URL: http://dx.doi.org/10.1039/c3sc53102c

Abstract

An efficient, robust and highly enantioselective catalytic desymmetrization of 2,2-disubstituted cyclopentene-1,3-diones is developed via direct vinylogous nucleophilic addition of deconjugated butenolides. A remarkable influence of the secondary catalyst site on the enantioselectivity points towards an intriguing mechanistic scenario, possibly by triggering a change in catalyst conformation.

Item Type: Journal Article
Additional Information: Copyright for this article belongs to the ROYAL SOC CHEMISTRY, ENGLAND
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Depositing User: Id for Latest eprints
Date Deposited: 12 May 2014 05:36
Last Modified: 12 May 2014 05:36
URI: http://eprints.iisc.ac.in/id/eprint/48922

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