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Form and Function of Proteins. Historical Background and the Indian Effort in Macromolecular Crystallography

Vijayan, M (2013) Form and Function of Proteins. Historical Background and the Indian Effort in Macromolecular Crystallography. In: NATIONAL ACADEMY SCIENCE LETTERS-INDIA, 36 (6). pp. 645-652.

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Official URL: http://dx.doi.org/10.1007/s40009-013-0220-5


Global efforts in macromolecular crystallography started in the thirties of the last century. However, definitive results began to emerge only in the late fifties and the early sixties. India has a long tradition in crystallography. The country had a head start in theoretical and computational structural biology, thanks to the efforts of G.N. Ramachandran and his colleagues in the fifties and the sixties. However, macromolecular crystallography got off the ground in India only in the eighties, particularly after the Bangalore group received adequate support from the Department of Science and Technology under their Thrust Area Programme. The Bangalore centre was also identified as a national nucleus for the development of the area in the country. Since then work in the area has spread widely and is being carried out by several groups, mainly led by scientists trained at Bangalore or their descendents, in about thirty institutions in India. In addition to the Department of Science and Technology, the effort is now supported by other agencies like the Department of Biotechnology and the Council of Scientific and Industrial Research. The problems addressed by macromolecular crystallographers in India encompass almost all aspects of modern biology. Indian efforts in macromolecular crystallography have also become an important component of the international efforts in the area.

Item Type: Journal Article
Additional Information: Copyright for this article belongs to NATL ACAD SCIENCES INDIA,INDIA
Keywords: Structural biology; Protein crystallography; Protein structure; Indian science; History of science
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Depositing User: Id for Latest eprints
Date Deposited: 23 Jan 2014 05:38
Last Modified: 23 Jan 2014 05:38
URI: http://eprints.iisc.ac.in/id/eprint/48220

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