Gautam, Rekha and Vanga, Sandeep and Madan, Aditi and Nongthomba, Upendra and Umapathy, Siva (2013) Classification of Myopathies on Molecular basis in Drosophila using Raman spectroscopy. In: FOURTH ASIAN SPECTROSCOPY CONFERENCE, 15-18 December, 2013, NTU, Singapore. (Submitted)
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Abstract
Myopathies are muscular diseases in which muscle fibers degenerate due to many factors such as nutrient deficiency, infection and mutations in myofibrillar etc. The objective of this study is to identify the bio-markers to distinguish various muscle mutants in Drosophila (fruit fly) using Raman Spectroscopy. Principal Components based Linear Discriminant Analysis (PC-LDA) classification model yielding >95% accuracy was developed to classify such different mutants representing various myopathies according to their physiopathology.
| Item Type: | Conference Poster |
|---|---|
| Keywords: | Raman Spectroscopy, Principal Component Analysis, Linear Discriminant Analysis, Drosophila, myopathy |
| Department/Centre: | Division of Biological Sciences > Molecular Reproduction, Development & Genetics Division of Chemical Sciences > Inorganic & Physical Chemistry |
| Date Deposited: | 05 Nov 2013 07:39 |
| Last Modified: | 06 Nov 2013 06:16 |
| URI: | http://eprints.iisc.ac.in/id/eprint/47708 |
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