Enantiospecific total synthesis of indole alkaloids (+)-eburnamonine, (-)-aspidospermidine and (-)-quebrachamine

Nidhiry, John Eugene and Prasad, Kavirayani R (2013) Enantiospecific total synthesis of indole alkaloids (+)-eburnamonine, (-)-aspidospermidine and (-)-quebrachamine. In: Tetrahedron, 69 (26). pp. 5525-5536.

PDF Tetr_69-26_5525_2013.pdf - Published Version Restricted to Registered users only Download (1MB) | Request a copy

Abstract

An enantiospecific total synthesis of indole alkaloids eburnamonine, aspidospermidine and quebrachamine is described from lactic acid. Synthesis of all three alkaloids is accomplished from a single chiral building block. Johnson-Claisen rearrangement of a chiral allyl alcohol is the main feature for the installation of the required quaternary centre.

Item Type:	Journal Article
Publication:	Tetrahedron
Publisher:	Elsevier Science
Additional Information:	Copyright of this article belongs to Elsevier Science.
Keywords:	Indole Alkaloids; Total Synthesis; Enantiospecific Synthesis; Claisen Rearrangement
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	03 Sep 2013 06:48
Last Modified:	03 Sep 2013 06:48
URI:	http://eprints.iisc.ac.in/id/eprint/46964

Actions (login required)

View Item