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NIS-Catalyzed Reactions: Amidation of Acetophenones and Oxidative Amination of Propiophenones

Lamani, Manjunath and Prabhu, Kandikere Ramaiah (2012) NIS-Catalyzed Reactions: Amidation of Acetophenones and Oxidative Amination of Propiophenones. In: CHEMISTRY-A EUROPEAN JOURNAL, 18 (46). pp. 14638-14642.

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Official URL: http://dx.doi.org/10.1002/chem.201202703

Abstract

Single-step amination: The N-iodosuccinimide (NIS)-catalyzed amidation of acetophenone derivatives by using tert-butylhydroperoxide (TBHP) as an oxidant is presented. A variety of acetyl derivatives of heterocyclic compounds were easily converted to their corresponding ketoamides under these conditions. A new, NIS-catalyzed amination of propiophenone and its derivatives in the presence of TBHP to furnish the corresponding 2-aminoketone derivatives is the first reported single-step amination of propiophenone derivatives.

Item Type: Journal Article
Additional Information: Copyright for this article belongs to WILEY-V C H VERLAG GMBH, GERMANY
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Depositing User: Francis Jayakanth
Date Deposited: 31 Dec 2012 05:25
Last Modified: 31 Dec 2012 05:25
URI: http://eprints.iisc.ac.in/id/eprint/45471

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