Analysis of integrated optofluidic lab-on-a-chip fluorescence biosensor based on transmittance of light through a fluidic gap

Krishnaswamy, Narayan and Srinivas, T and Rao, Mohan G (2011) Analysis of integrated optofluidic lab-on-a-chip fluorescence biosensor based on transmittance of light through a fluidic gap. In: 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society,EMBC, Aug. 30 2011-Sept. 3 2011, Boston, MA, USA.

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Abstract

Sensitivity analysis is an important aspect to be looked into while designing lab-on-a-chip systems. In this paper we will be showing with appropriate design that the best sensitivity of the fluorescence biosensor is achieved for an optimal width of fluidic gap, corresponding to a particular mode spot size. We will be also showing that the sensitivity of the biosensor is affected by efficiency of light coupling, which is influenced by changes in the width of fluidic gap, refractive index of the fluid and higher order modes.

Item Type:	Conference Paper
Publisher:	IEEE
Additional Information:	Copyright 2011 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
Department/Centre:	Division of Physical & Mathematical Sciences > Instrumentation Appiled Physics
Date Deposited:	23 Dec 2011 05:33
Last Modified:	23 Dec 2011 05:33
URI:	http://eprints.iisc.ac.in/id/eprint/42875

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