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Contraceptive vaccines: current status and problems in mass application

Rao, Jagannadha A (2011) Contraceptive vaccines: current status and problems in mass application. In: Current Science (Bangalore), 100 (5). pp. 661-670.

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Progress in the development of contraceptive vaccines for males and females is reviewed. Based on the criteria which need to be met with, none of the proposed candidate antigens meets the requirements for use as a contraceptive vaccine for human application. One of the major problems is the need for periodic injections to maintain required titre and use of an alternate method until effective titres are obtained. Some of the problems associated with active immunization approach can be overcome by the use of preformed, highly specific, potent antibodies. Some progress has been achieved in this direction by the use of humanized single chain monoclonal antibodies to human chorionic gonadotropin.

Item Type: Journal Article
Publication: Current Science (Bangalore)
Publisher: Indian Academy of Sciences
Additional Information: Copyright of this article belongs to Indian Academy of Sciences.
Keywords: Contraceptive vaccines; fertility control; hormones; reproduction
Department/Centre: Division of Biological Sciences > Biochemistry
Date Deposited: 05 Apr 2011 07:34
Last Modified: 05 Apr 2011 07:34
URI: http://eprints.iisc.ac.in/id/eprint/36607

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