Prasad, Kavirayani R and Gandi, Vasudeva Rao (2010) Formal total synthesis of (+)-didemniserinolipid B. In: Tetrahedron: Asymmetry, 21 (23). pp. 2848-2852.
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Official URL: http://dx.doi.org/10.1016/j.tetasy.2010.11.006
Abstract
The formal total synthesis of (+)-didemniserinolipid B, a marine tunicate possessing a 6,8-dioxabicyclo3.2.1]octane framework, was accomplished starting from L-(+)-tartaric acid. The key transformations in the synthesis include the elaboration of a gamma-hydroxy-amide readily obtained by desymmetrization of tartaric acid bis-amide via the controlled addition of a Grignard reagent followed by stereoselective reduction of the resulting ketone. (C) 2010 Elsevier Ltd. All rights reserved.
| Item Type: | Journal Article |
|---|---|
| Publication: | Tetrahedron: Asymmetry |
| Publisher: | Elsevier Science |
| Additional Information: | Copyright of this article belongs to Elsevier Science. |
| Department/Centre: | Division of Chemical Sciences > Organic Chemistry |
| Date Deposited: | 12 Apr 2011 09:11 |
| Last Modified: | 12 Apr 2011 09:11 |
| URI: | http://eprints.iisc.ac.in/id/eprint/35965 |
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