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Synthesis and Isolation of 5,6-Dihydro-4H-1,3-Oxazine Hydrobromides by Autocyclization of N-(3-Bromopropyl)amides

Reddy, Damodara N and Prabhakaran, Erode N (2011) Synthesis and Isolation of 5,6-Dihydro-4H-1,3-Oxazine Hydrobromides by Autocyclization of N-(3-Bromopropyl)amides. In: Journal of Organic Chemistry, 76 (2). pp. 680-683.

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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo101955q

Abstract

5,6-Dihydro-4H-1,3-oxazine hydrobromides have been synthesized by the nucleophilic autocyclo-O-alkylation of N-(3-bromopropyl)amides under neutral conditions in chloroform. It is found that electron-donating amide alpha-substituents influence the autocyclization efficiency.

Item Type: Journal Article
Publication: Journal of Organic Chemistry
Publisher: American Chemical Society
Additional Information: Copyright of this article belongs to American Chemical Society.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Date Deposited: 04 Mar 2011 06:43
Last Modified: 04 Mar 2011 06:43
URI: http://eprints.iisc.ac.in/id/eprint/35808

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