The stereochemistry of a-aminoisobutyric acid containing peptides

Venkataram Prasad, BV and Balaram, Padmanabhan and Benedetti, Etlore (1984) The stereochemistry of a-aminoisobutyric acid containing peptides. In: Critical Reviews in Biochemistry and Molecular Biology, 16 (4). pp. 307-348.

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Abstract

a-Aminoisobutyric acid (Aib), * a nonprotein amino acid first described synthetically, I has been found in diverse sources, ranging from peptides of microbial origin2s3 to the Murchison mete~r i te.E~a rly studies of the chemistry of Aib were directed towards the synthesis of model peptides containing this "sterically hindered" amino There have been several reports on the synthesis of Aib containing analogs of biologically active peptides.

Item Type:	Journal Article
Publication:	Critical Reviews in Biochemistry and Molecular Biology
Publisher:	Informa Plc
Additional Information:	Copyright of this article belongs to Informa Plc.
Department/Centre:	Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited:	29 Oct 2010 06:03
Last Modified:	29 Oct 2010 06:03
URI:	http://eprints.iisc.ac.in/id/eprint/33476

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