Polycyclitols. Novel conduritol and carbasugar hybrids as a new class of potent glycosidase inhibitors

Mehta, Goverdhan and Ramesh, Senaiar S (2000) Polycyclitols. Novel conduritol and carbasugar hybrids as a new class of potent glycosidase inhibitors. In: Chemical Communications (24). pp. 2429-2430.

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Abstract

We have conceptualized new molecular entities (bicyclitols) in which two conduritol and two carbasugar moieties are embedded in a polyhydroxylated decahydronaphthalene framework and achieved their syntheses in a stereo- and regioselective manner. One of the bicyclitols was found to be a potent and selective \alpha-glucosidase inhibitor.

Item Type:	Journal Article
Publication:	Chemical Communications
Publisher:	The Royal Society of Chemistry
Additional Information:	Copyright for this article belongs to The Royal Society of Chemistry.
Department/Centre:	Division of Chemical Sciences > Organic Chemistry
Date Deposited:	02 Feb 2005
Last Modified:	19 Sep 2010 04:17
URI:	http://eprints.iisc.ac.in/id/eprint/2692

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