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A fluorescent probe study of the solubilisation of cholesterol by biie salt-phospholipid micelles

Paul, Ranajit and Balaram, P (1978) A fluorescent probe study of the solubilisation of cholesterol by biie salt-phospholipid micelles. In: Biochemical and Biophysical Research Communications, 81 (3). pp. 850-857.

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Abstract

The fluorescent probe dansyl cadaverine has been shown to bind strongly to mixed bile salt-phospholipid micelles containing unsaturation in the fatty acyl chains. Incorporation of cholesterol into the mixed micelles reduces the number of molecules of bound dansyl cadaverine without altering the binding affinity. These results suggest a tighter packing of the hydrocarbon matrix of the micelles in the presence of cholesterol.

Item Type: Journal Article
Publication: Biochemical and Biophysical Research Communications
Publisher: Elsevier Science
Additional Information: Copyright of this article belongs to Elsevier Science
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Date Deposited: 11 Dec 2009 07:32
Last Modified: 19 Sep 2010 05:52
URI: http://eprints.iisc.ac.in/id/eprint/24898

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