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Facile Entry into Triazole Fused Heterocycles via Sulfamidate Derived Azido-alkynes

Sudhir, V Sai and Kumar, NY Phani and Baig, RB Nasir and Chandrasekaran, Srinivasan (2009) Facile Entry into Triazole Fused Heterocycles via Sulfamidate Derived Azido-alkynes. In: Journal of Organic Chemistry, 74 (19). pp. 7588-7591.

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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo9016748


Direct synthesis of condensed triazoles from diverse sulfamidates by ring opening of sulfamidates with sodium azide followed by one-pot propargylation and cycloaddition furnished title compounds. The methodology in general has been demonstrated on diverse sulfamidates derived from amino acids, amino acid derivatives, and carbohydrates to obtain diverse triazole fused scaffolds. In one example, a condensed triazole containing amino acid has been synthesized by ring opening of a sulfamidate derivative with propargyl amine.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to American Chemical Society, 2009.
Department/Centre: Division of Chemical Sciences > Organic Chemistry
Depositing User: Id for Latest eprints
Date Deposited: 17 Dec 2009 11:09
Last Modified: 19 Sep 2010 05:49
URI: http://eprints.iisc.ac.in/id/eprint/24215

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