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Sequence effects in structures of the dinucleotides d-pApT AND d-pTpA

Hosur, Ramakrishna V and Govi, Girjesh and Hosur, Madhusoodan V and Viswamitra, MA (1981) Sequence effects in structures of the dinucleotides d-pApT AND d-pTpA. In: Journal of Molecular Structure, 72 (Mar). pp. 261-267.

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Official URL: http://adsabs.harvard.edu/abs/1981JMoSt..72..261H

Abstract

The H1',H2' and H2″ regions of the 270-MHz PMR spectra of two deoxydinucleotides, d-pTpA and d-pApT, have been analyzed. The coupling constants in the sugar ring indicate that both A and T sugars have a tendency to acquire 2E conformations. There is also a marginal difference in the 2E populations of the T sugar in the two dinucleotides. The trends in the chemical shifts of base protons indicate different stacking of the bases in d-pApT and d-pTpA. The sequence effects on base stacking and pentose conformation are discussed.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to Elsevier Science.
Department/Centre: Division of Physical & Mathematical Sciences > Physics
Depositing User: Manjula Kadadallimath
Date Deposited: 24 Dec 2009 09:31
Last Modified: 19 Sep 2010 05:47
URI: http://eprints.iisc.ac.in/id/eprint/23767

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