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Identification of amino groups in the carbohydrate binding activity of winged bean acidic agglutinin

Sajjan, SU and Patanjali, SR and Surolia, A (1997) Identification of amino groups in the carbohydrate binding activity of winged bean acidic agglutinin. In: 4th International Symposium on Biochemical Role of Eukaryotic Cell Surface Macromolecules, JAN 06-10, 1996, NEW DELHI, INDIA, pp. 76-81.

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Abstract

Chemical modification studies reveal that the modification of amino groups in WBA II leads to a complete loss in the hemagglutinating and saccharide binding activities. Since WBA II is a dimeric molecule and contains two binding sites, one amino group in each of the binding sites is inferred to be essential for its activity. The presence of amino group which has a potential to form hydrogen bonded interactions with the ligand, substantiates our observation regarding the forces involved in WBA II-receptor and WBA II-simple sugar interactions.

Item Type: Conference Paper
Additional Information: Copyright of this article belongs to National Institute of Science Communication and Information Resources.
Department/Centre: Division of Biological Sciences > Molecular Biophysics Unit
Depositing User: Mr. S Muthuraja
Date Deposited: 17 Aug 2009 06:27
Last Modified: 17 Aug 2009 06:27
URI: http://eprints.iisc.ac.in/id/eprint/19522

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