ePrints@IIScePrints@IISc Home | About | Browse | Latest Additions | Advanced Search | Contact | Help

Antiviral activity of liposome-encapsulated cupric complex of isonicotinic acid hydrazide against avian myeloblastosis virus infection

Vasudevachari, MB and Antony, A (1985) Antiviral activity of liposome-encapsulated cupric complex of isonicotinic acid hydrazide against avian myeloblastosis virus infection. In: Indian Journal of Experimental Biology, 23 (7). pp. 393-396.

Full text not available from this repository. (Request a copy)

Abstract

Cupric complex of isonicotinic acid hydrazide (cupric-INH complex) has been shown to inactivate avian myeloblastosis virus (AMV). The complex did not have any demonstrable chemotherapeutic activity against AMV infection in chicks. However, when encapsulated in positive charged liposomes the complex partially protected the chicks from AMV infection. The levels and stability of the complex in various tissues particularly in bone marrow, the target tissue for AMV multiplication, were higher in liposome-encapsulated cupric-INH complex injected than in chicks injected with unencapsulated complex.

Item Type: Journal Article
Additional Information: Copyright of this article belongs to National Institute of Science Communication and Information Resources.
Department/Centre: Division of Biological Sciences > Microbiology & Cell Biology
Depositing User: RM Shivakumara
Date Deposited: 11 Jul 2008
Last Modified: 27 Aug 2008 13:34
URI: http://eprints.iisc.ac.in/id/eprint/14971

Actions (login required)

View Item View Item